Scholarly PublicationJumbri, K. and Ahmad, H. and Abdulmalek, E. and Rahman, M.B.A. (2016) Biophysical properties of DNA in hydrated ionic liquids. In: UNSPECIFIED.
Full text not available from this repository.Abstract
The biophysical properties and behavior of natural calf thymus DNA in hydrated 1-ethyl-3-butylimidazolium bromide ionic liquid (C2bimBr) have been studied using spectroscopy technique. The effect of ionic liquid concentration and temperature towards the duplex B-DNA conformation were determined. The presence of ionic liquid causes higher duplex DNA stability with the DNA melting temperature of �56°C without any addition of buffer solutions. The electrostatic attraction between ionic liquid's cation and DNA phosphates groups was found play a main role in stabilizing native DNA structure. Understanding of the biophysical properties of DNA in this ionic media could be used as a platform for future development of specific solvent for nucleic acid nanotechnology. © 2016 Author(s).
| Item Type: | Conference or Workshop Item (UNSPECIFIED) |
|---|---|
| Impact Factor: | cited By 2 |
| Depositing User: | Ms Sharifah Fahimah Saiyed Yeop |
| Date Deposited: | 25 Mar 2022 07:12 |
| Last Modified: | 25 Mar 2022 07:12 |
| URI: | http://scholars.utp.edu.my/id/eprint/30593 |
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